The 21st-century reality has clearly demonstrated that current pupils will work in jobs that don’t exist right now; most importantly, they are also the ones who will create those jobs. That‘s why this Strategic Partnership has been built up around the firm belief that entrepreneurship, as the project title suggests, does matter as a key competence for lifelong learning. The Partnership‘s main goal is to develop pupils‘ entrepreneurial skills as a counteract to youth unemployment and to provide support to their less stressful transition to adulthood. Secondary schools from Bulgaria, Greece, Italy, Austria, Portugal and Romania are planning to involve our target groups of teens (aged 14-18) in a number of challenging, mixed-reality activities whose purpose will be to empower them with the competences needed for their various career paths. In order to achieve our goal, we are targeting the tourism sector as the main job provider in our regions.