“Modern Education in Science for Industry 4.0” was a two year international project that opened education and innovative practices in the digital era, in which current trends of data exchange, the internet, cloud computing, STEM contents (Science, Technology, Engineering and Mathematics) were integrated in the field of Industry 4.0. MESI4.0 was a cooperation of four schools: Gymnazium Teplice (CZ), Colegio La Salle-Buen Consejo (ES), Geswichte Schole Bremerhaven (DE) and Didzdvario gymnasium (LT). The consortium was a team of educators of STEM subjects, English and Geography and students aged from 14 to 18 years old.